Frameshift mutation has no effect on amino acid sequence in protein synthesis.

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A second major type of mutation is the frameshift mutation. This alteration involves the insertion or deletion of one or more base pairs to the DNA molecule. As Figure 4-4 shows, these mutations can change the entire "reading frame" of the DNA sequence because codons consist of groups of three base pairs. A frameshift mutation thus can greatly alter the resulting amino acid sequence.

Frameshift Mutation Has No Effect on Amino Acid Sequence in Protein