A shift to the left describes the premature release of immature neutrophils when the demand for mature neutrophils exceeds the supply.

Question

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When the demand for circulating mature neutrophils exceeds the supply, the marrow begins to release immature neutrophils (and other leukocytes) into the blood. Premature release of the immature white cells is responsible for the phenomenon known as a shift to the left or leukemoid reaction.

A Shift to the Left Describes the Premature Release of Immature