What is the primary mechanism of atherogenesis?
A)The release of the inflammatory cytokines tumor necrosis factor-alpha (TNF-α), interferon-gamma (IFN-γ), and interleukin-1 (IL-1)
B)The release of the growth factor granulocyte-macrophage colony-stimulating factor (GM-CSF)
C)The release of toxic oxygen radicals that oxidize low-density lipoproteins (LDLs)
D)The release of the inflammatory cytokines interferon-beta (IFN-β), interleukin-6 (IL-6), and granulocyte colony-stimulating factor (G-CSF)

Question

Quizplus · Accepted Answer

The oxidation of LDL is an important step in atherogenesis. Inflammation with oxidative stress and activation of macrophages is the primary mechanism.

What Is the Primary Mechanism of Atherogenesis