In terms of the number of premature deaths per year and reduced life span, the greatest risk, by far, is malaria.

Question

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Malaria is responsible for the greatest number of premature deaths per year, particularly in sub-Saharan Africa. It is estimated that malaria kills over 400,000 people annually, most of whom are young children in Africa. Additionally, even for those who survive malaria, the disease can cause long-term health problems and reduced life expectancy. Therefore, malaria poses the greatest risk in terms of premature deaths and reduced life span.

In Terms of the Number of Premature Deaths Per Year