Evidence indicates that early analgesia reduces postoperative problems.Recent studies endorse the multimodal approach to both preemptive (preventative) and postoperative analgesia customized to patient needs based on meticulous preoperative assessment.A 72-year-old physically active woman was seen in the preoperative admission center in preparation for her total knee replacement surgery on Thursday.She has not had any opioid medications in her lifetime that she can remember.She has inflammatory bowel and gastric disease and was told she cannot take ibuprofen in any form.Select a multimodal analgesic treatment plan that would best serve the patient's perianesthesia experience.
A) Intraoperative: Preincision-IV opioids, local lidocaine injection into the incision site before skin closure. Postoperative: Patient-controlled analgesia (PCA) with opioids and nonsteroidal anti-inflammatory drugs (NSAIDs)
B) Intraoperative: Preincision-regional block, IV opioids during the procedure. Postoperative: PCA with opioids and nonsteroidal anti-inflammatory drugs (NSAIDs)
C) Intraoperative: Spinal anesthesia with femoral nerve block. Postoperative: Systemic analgesia with COX-2-selective inhibitors, IV PCA with strong opioids
D) Intraoperative: Spinal anesthesia with femoral nerve block. Postoperative: Systemic analgesia with COX-2-selective inhibitors, IV PCA with strong opioids (titrated to effect) , and IM meperidine
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