In what level of the biofilm do the organisms downregulate very efficiently and are the least metabolically active?

Name: In what level of the biofilm do the organisms downregulate very efficiently and are the least metabolically active?
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Quizplus · Accepted Answer

The innermost layer of cells is attached to the substratum and represents the earliest part of the biofilm.These microorganisms also downregulate very efficiently and are the least metabolically active.This is where most of the persister cells are located.

In What Level of the Biofilm Do the Organisms Downregulate