Penicillins,cephalosporins,monobactams,and carbapenems all have this ring in their structure that is responsible for inhibiting the transpeptidation reaction,resulting in bacterial lysis and cell death.

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The active moiety of β-lactam antibiotics is the four-membered β-lactam ring-a ring structure found in penicillins,cephalosporins,monobactams,and carbapenems.The four-membered ring represented by the structure labeled β-lactam functions as a structural analogue of the normal substrate,and inhibits the transpeptidation reaction,resulting in bacterial lysis and cell death.

Penicillins,cephalosporins,monobactams,and Carbapenems All Have This Ring in Their Structure That