What are the primary uses of flow cytometry in the evaluation of hematologic disorders?

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Flow cytometry is commonly used to detect the presence of clonality and diagnose and classify malignant lymphomas and leukemias. This technique allows for the identification of aberrant populations of cells based on their surface markers and can aid in distinguishing between different subtypes of hematologic malignancies.

B, C, and D are also possible uses of flow cytometry in the evaluation of hematologic disorders, but are less commonly used than A. Flow cytometry can be utilized to classify anemias associated with defective hemoglobin synthesis by analyzing the presence and distribution of abnormal red blood cells. It can also be used to identify specific genetic rearrangements in hematologic malignancies, and to detect chromosomal alterations such as aneuploidy or translocations.

What Are the Primary Uses of Flow Cytometry in the Evaluation