The aPTT is the most common procedure used to monitor the unfractionated heparin therapy.Which of the reagents used in the testing provides the activation of the formation of the fibrin clot?

Question

Quizplus · Accepted Answer

The reagents used in the aPTT testing include phospholipid-rich substances (e.g. cephalin) and contact activators (e.g. ellagic acid or kaolin) that initiate the intrinsic pathway of coagulation. Calcium ions are also added to promote coagulation factor activation and ultimately lead to the formation of a fibrin clot. Therefore, the correct answer is B, as it includes the activation of the partial thromboplastin complex and calcium. Thromboplastin (A) activates the extrinsic pathway, while thrombin (C) and normal pooled plasma (D) are not used in the aPTT testing.

The APTT Is the Most Common Procedure Used to Monitor