Question 1

Individuals with Huntington disease have a point mutation in a gene coding for the p53 protein.

Accepted Answer

This statement is false. Huntington disease is caused by a mutation in the HTT gene, not the p53 gene. The protein produced by the HTT gene, called huntingtin, accumulates abnormally in the brain and causes motor, cognitive, and psychiatric symptoms.

Question 2

The availability of a large series of monozygotic and dizygotic twins often enhances studies on the genetic basis of human behavior.

Accepted Answer

Monozygotic twins share 100% of their genetic material while dizygotic twins share 50%, making twin studies helpful for investigating the genetic components of behavior.

Question 3

Drosophila can learn and remember.

Accepted Answer

Studies have shown that Drosophila can learn and remember various tasks such as odor discrimination, classical conditioning, and operant conditioning. They have also been used as a model organism to study the biological basis of memory and learning.

Question 4

In studies attempting to determine a genetic basis for a given behavior,if the environment is held constant,and behavioral differences directly correlate with genetic differences,a genetic basis for the behavioral state is supported.

Accepted Answer

If behavioral differences can be attributed to genetic differences when the environmental conditions are held constant, then it supports the idea that there is a genetic basis for the behavior being studied.

Question 5

Research on alcoholism indicates that at least in mouse and animal models,a single dominant gene is responsible.

Accepted Answer

While genetics certainly play a role in the development of alcoholism, it is a complex disease with multiple genetic and environmental factors involved. There is no single gene that has been identified as a dominant cause of alcoholism in humans.

Question 6

Evidence from genome-wide association studies on schizophrenia indicates that no single gene or allele makes a significant contribution to this disorder.

Accepted Answer

Genome-wide association studies on schizophrenia have failed to find a single gene or allele that makes a significant contribution to the disorder. Schizophrenia is believed to be a complex disorder caused by a combination of genetic and environmental factors.

Question 7

The symptoms of Huntington disease usually appear in the third to fifth decade of life in humans.

Accepted Answer

The symptoms of Huntington disease usually appear in the third to fifth decade of life in humans.

Question 8

A transgenic mouse model now exists for Huntington disease in humans.

Accepted Answer

A transgenic mouse model for Huntington disease was first created in 1996 and has been used extensively in research on the disease.

Question 9

Mitochondrial ribosomes are responsible for determining the learning and memory development in Drosophila.

Accepted Answer

Mitochondrial ribosomes are involved in protein synthesis within mitochondria, not directly in determining learning and memory development in Drosophila or other organisms.

Quiz 24: Neurogenetics

Individuals with Huntington disease have a point mutation in a gene coding for the p53 protein.

The availability of a large series of monozygotic and dizygotic twins often enhances studies on the genetic basis of human behavior.

Drosophila can learn and remember.

In studies attempting to determine a genetic basis for a given behavior,if the environment is held constant,and behavioral differences directly correlate with genetic differences,a genetic basis for the behavioral state is supported.

Research on alcoholism indicates that at least in mouse and animal models,a single dominant gene is responsible.

Evidence from genome-wide association studies on schizophrenia indicates that no single gene or allele makes a significant contribution to this disorder.

The symptoms of Huntington disease usually appear in the third to fifth decade of life in humans.

A transgenic mouse model now exists for Huntington disease in humans.

Mitochondrial ribosomes are responsible for determining the learning and memory development in Drosophila.