Which of the following distinguishes lagging strand from leading strand synthesis during DNA replication?

Question

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The synthesis of the lagging strand during DNA replication produces short Okazaki fragments that need to be later joined together by DNA ligase. In contrast, the leading strand is continuously synthesized in the same direction as the replication fork movement, without the need for Okazaki fragments. The 5' to 3' direction, requirement for DNA polymerase, and requirement for DNA helicase are common to both leading and lagging strand synthesis.

Which of the Following Distinguishes Lagging Strand from Leading Strand