Most of the clinical symptoms observed in an individual with malaria result from this activity.

Question

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The lysis of red blood cells by merozoites is responsible for the majority of clinical symptoms associated with malaria, including fever, anemia, and organ damage. Sporozoite infection of the liver (Option A) occurs early on in the infection, but does not produce noticeable symptoms. Sporozoite infection of muscle (Option B) is relatively rare and not typically associated with clinical symptoms. Infection of white blood cells by merozoites (Option D) is also not usually associated with noticeable symptoms. Parasite infection of the brain cells (Option E) can lead to severe neurological symptoms, but this only occurs in severe cases of malaria (e.g. cerebral malaria) and is not a common symptom of the infection.

Most of the Clinical Symptoms Observed in an Individual with Malaria