More than 50% of all cancers involve an acquired mutation in the tumor suppressor gene _____.

Question

Quizplus · Accepted Answer

p53 is a commonly mutated tumor suppressor gene in many types of cancer. In fact, it is estimated that more than 50% of all cancers involve a mutation in the p53 gene. Mutations in BRCA1 and BRCA2 are associated with an increased risk of breast and ovarian cancer, but they are not as common as p53 mutations. Antigen 125 is not a tumor suppressor gene, but rather a biomarker used to monitor ovarian cancer.

More Than 50% of All Cancers Involve an Acquired Mutation