Which of the following parameters have been suggested as indications for pediatric ECMO? I.PaO₂

Question

Which of the following parameters have been suggested as indications for pediatric ECMO?
I.PaO₂ < 50 mm Hg
II.PaO₂/FiO₂ < 75
III.OI > 35
IV.Pre-ECMO pH < 7.20

Quizplus · Accepted Answer

There is no definitive consensus on when ECMO should be initiated in pediatric respiratory failure.Single-center reviews have attempted to identify pre-ECMO factors that may help predict outcome.Mehta and colleagues suggested that an OI > 35 or a pre-ECMO pH of < 7.20 may result in higher mortality.In a case series by Turner and colleagues,it was suggested that there are no true contraindications to using ECMO in pediatric patients with refractory respiratory failure.They further commented that ECMO is appropriate if patients are transferred to an ECMO center early,if lung-protective ventilation is used,and when severe neurologic injury is not present.A PaO₂/FiO₂ ratio of < 200 mm Hg is one criteria used to identify patients with ARDS.In severe cases the PaO₂/FiO₂ ratio may be < 75 and mortality risk exceeds 80%-a point when ECMO is considered.

Which of the Following Parameters Have Been Suggested as Indications