Which gene is the most important suppressor gene? It is inactive until DNA in the cell's nucleus is damaged?

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Quizplus · Accepted Answer

The most important suppressor gene is p53. It functions as a tumor suppressor gene, and when there is damage to DNA, it is activated to halt the cell cycle, allowing for DNA repair. If the damage cannot be repaired, p53 can initiate processes that lead to programmed cell death (apoptosis). Mutations in the p53 gene can lead to uncontrolled cell growth and the development of cancer. Her2/neu and CEA are oncogenes (genes that promote uncontrolled cell growth), and BRCA is a tumor suppressor gene that is primarily associated with breast cancer.

Which Gene Is the Most Important Suppressor Gene? It Is