If a pharmacologist wanted to develop a sleep-inducing drug that did not reduce anxiety,which site should she target the drug for?

Question

Quizplus · Accepted Answer

The BZ 1 site is responsible for the sedative effects of benzodiazepines and other sleep-inducing drugs, without reducing anxiety. Targeting this site would result in a drug that promotes sleep without causing a reduction in anxiety levels. The BZ 2 site is responsible for the anxiolytic effects of benzodiazepines, so targeting this site may result in a reduction in anxiety as well. The barbiturate and ethanol sites are not specific enough to produce a sleep-inducing drug that does not reduce anxiety.

If a Pharmacologist Wanted to Develop a Sleep-Inducing Drug That