In allergic contact dermatitis, which cells possess the antigens and present them to T cells?
A)Langerhans cells
B)Merkel cells
C)Keratinocytes
D)Macrophages

Question

Quizplus · Accepted Answer

In allergic contact dermatitis, Langerhans cells process the antigen and carry it to T cells that then become sensitized to the antigen-releasing cytokines and chemokines, leading to leukocyte infiltration and inflammation. Merkel cells are associated with touch receptors and function as slowly adapting mechanoreceptors when stimulated by deformation of the epidermis. Keratinocytes produce keratin, a scleroprotein that provides protection from mechanical stress. Keratin is the main constituent of skin, hair, and nail cells.

In Allergic Contact Dermatitis, Which Cells Possess the Antigens and Present