A reversal of the normal serum albumin/globulin (A/G)ratio occurs in ____ disease.

Question

Quizplus · Accepted Answer

Kidney and liver disease are the two major causes of decreased serum albumin ratios.The liver is the site of albumin synthesis such that damage to this organ will decrease serum albumin,whereas kidney damage results in urinary loss of albumin.In both instances,when disease has progressed significantly,the ratio becomes less than the normal 2:1.The globulin component may be increased or decreased in various conditions,including chronic inflammation and monoclonal immunoglobulin disease.These conditions will also alter the A/G ratio.

A Reversal of the Normal Serum Albumin/globulin (A/G)ratio Occurs in ____