A 58 year old woman noted a mass in her breast,for which she sought advice from her GP.The physician felt the mass,but also noticed skin retraction over the lesion.A biopsy was done,revealing the histological appearance shown in the accompanying low power photomicrograph.Which one of the following is the best diagnosis?

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The history suggests a malignant diagnosis.Infiltrating ductal carcinoma is the most common,statistically,and the histological appearance confirms infiltrating ductal structures (D)and a reactive fibrous stroma (St).Skin retractions are also quite common in infiltrating ductal carcinomA

A 58 Year Old Woman Noted a Mass in Her