A 55 year old former long-distance runner consulted his GP because of pain in his knee.The joint space was severely narrowed,and the pain was "intolerable".Knee replacement was done.A sample of the tissue removed is shown in the accompanying photomicrograph.Which one of the following is the best diagnosis?
A)Gout
B)Osteomalacia
C)Osteoporosis
D)Osteoarthritis
E)Rheumatoid arthritis

Question

A 55 year old former long-distance runner consulted his GP because of pain in his knee.The joint space was severely narrowed,and the pain was "intolerable".Knee replacement was done.A sample of the tissue removed is shown in the accompanying photomicrograph.Which one of the following is the best diagnosis? 
A)Gout 
B)Osteomalacia 
C)Osteoporosis 
D)Osteoarthritis 
E)Rheumatoid arthritis

Quizplus · Accepted Answer

The photo on the left shows fraying of the cartilage surface,and the right photo shown fibrosis and thickening of the sub-articular bonEThis is most consistent with osteoarthritis,which is typically a disease of large joints,especially in people that are obese,or have put unusual stresses on their joints,such as long-distance runners.

A 55 Year Old Former Long-Distance Runner Consulted His GP