Inhalation of allergenic pollen in a susceptible person causes the induction of what primary event, triggering an allergy reaction?
A) crosslinking of IgE-sensitized mast cells
B) immediate anaphylaxis
C) binding to sensitized cytotoxic T cells
D) increased cAMP levels
E) immediate leukotriene release

Question

Quizplus · Accepted Answer

Inhalation of allergenic pollen in a susceptible person can lead to the binding of the allergen to IgE antibodies on the surface of mast cells. This crosslinking of IgE-sensitized mast cells triggers the release of inflammatory mediators such as histamine, leading to the symptoms of an allergic reaction. Therefore, the primary event triggering an allergy reaction is the crosslinking of IgE-sensitized mast cells.

Inhalation of Allergenic Pollen in a Susceptible Person Causes the Induction