What datum from an amniocentesis indicates a neural tube defect?

Name: What datum from an amniocentesis indicates a neural tube defect?
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An increase in alpha-fetoprotein (AFP) in the amniotic fluid or maternal serum can indicate a neural tube defect. AFP is normally produced by the fetal liver and yolk sac, but when there is an opening in the neural tube, more AFP leaks out into the amniotic fluid and crosses into the maternal bloodstream.

What Datum from an Amniocentesis Indicates a Neural Tube Defect