Match the disease with its chromosomal abnormality.
-An additional chromosome joining the normal homologous pair

Question

Quizplus · Accepted Answer

Down Syndrome is caused by an extra copy of chromosome 21, leading to a total of three copies instead of the normal two.

Answer: B
 Fragile X Syndrome is caused by a mutation in the FMR1 gene on the X chromosome, rather than a numerical or structural abnormality of the chromosomes.

Answer: C
 Klinefelter Syndrome is caused by an extra X chromosome in males, leading to a total of XXY instead of XY.

Answer: D
 Turner Syndrome is caused by a missing or partially missing X chromosome in females, leading to a total of only one X chromosome instead of the normal two.

Answer: E
 Cri du chat (or "cry of the cat") is caused by a deletion in chromosome 5, specifically in the region known as 5p- (meaning the short arm of chromosome 5 is missing a piece).

Match the Disease with Its Chromosomal Abnormality