After a partial gastrectomy or pyloroplasty,what causes clinical manifestations of increased pulse,hypotension,weakness,pallor,sweating,and dizziness?
A) An anaphylactic reaction in which chemical mediators,such as histamine,prostaglandins,and leukotrienes,relax vascular smooth muscles causing shock.
B) These clinical manifestations are caused by hemorrhage postoperatively in which a large volume of blood is lost causing hypotension with compensatory tachycardia.
C) A concentrated bolus moves from stomach into the small intestine,which causes hyperglycemia,resulting in polyuria and eventually hypovolemic shock.
D) A rapid gastric emptying and creation of a high osmotic gradient in the small intestine that causes a sudden shift of fluid from the blood vessels to the intestinal lumen.

Question

Quizplus · Accepted Answer

After a partial gastrectomy or pyloroplasty, the gastric emptying is much faster than normal, causing a concentrated bolus to pass into the small intestine, thus creating a high osmotic gradient. This causes a sudden shift of fluid from the blood vessels to the intestinal lumen, leading to hypovolemia, increased pulse, weak pulse, hypotension, weakness, pallor, sweating, and dizziness. This is also known as "dumping syndrome." Option A is not applicable as there is no evidence of anaphylaxis in the scenario. Option B is not applicable because the given symptoms are not enough to say whether there is a hemorrhage or not. Option C is not applicable as there is no connection between concentrated bolus moving towards small intestine to hyperglycemia.

After a Partial Gastrectomy or Pyloroplasty,what Causes Clinical Manifestations of Increased