Autoreceptors
A) are sensitive to the presence of neuropeptides in the synapse.
B) control the release of calcium ions from the axon terminal.
C) mostly facilitate neuron function.
D) are metabotropic in nature.
E) control the formation of new dendritic spines.

Question

Quizplus · Accepted Answer

Autoreceptors are metabotropic, meaning that they work through G-protein signaling pathways to alter the activity of the neuron. They are located on the presynaptic membrane and regulate the release of neurotransmitters. When neurotransmitter levels in the synapse reach a certain threshold, the autoreceptor detects this and signals the neuron to decrease its release of neurotransmitter. This is known as feedback inhibition and helps maintain proper levels of neurotransmitters in the synapse.