The binding of released histamine to a H1 (histamine 1) receptor during an allergic attack induces a proinflammatory state through which pathway(s)?

Question

Quizplus · Accepted Answer

The binding of histamine to H1 receptors induces the activation of various signaling pathways, including the lipoxygenase pathway and cyclooxygenase pathway, leading to the production of proinflammatory leukotrienes and prostaglandins. This results in the symptoms of an allergic reaction such as bronchoconstriction, vasodilation, and increased mucus production.

The Binding of Released Histamine to a H1 (Histamine 1)