Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format.
As a triage nurse in the ER, you begin the assessment of an elderly patient complaining of bloody diarrhea and severe stomach cramps. You find the patient has a fever of 104oF as well, and is showing signs of dehydration. IV fluids are administered while further analysis of the patient continues.
-Based upon the information you have received from the laboratory,you inform the patient of his condition.In doing so,you tell him that this infection may be difficult to treat with antibiotics.Which part of the cell envelope restricts the passage of many of these drugs into gram-negative bacteria?

Question

Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format.
  As a triage nurse in the ER, you begin the assessment of an elderly patient complaining of bloody diarrhea and severe stomach cramps. You find the patient has a fever of 104oF as well, and is showing signs of dehydration. IV fluids are administered while further analysis of the patient continues.
-Based upon the information you have received from the laboratory,you inform the patient of his condition.In doing so,you tell him that this infection may be difficult to treat with antibiotics.Which part of the cell envelope restricts the passage of many of these drugs into gram-negative bacteria?

Quizplus · Accepted Answer

The outer membrane layer in gram-negative bacteria restricts the passage of many drugs, including antibiotics, due to its unique structure comprised of lipopolysaccharides and porins. Peptidoglycan and the cell membrane are present in both gram-negative and gram-positive bacteria, but do not restrict antibiotic passage to the same extent as the outer membrane layer.

Please Read the Clinical Scenario, and Then Answer the Question