Sheree is referred to a genetic counselor because a cystic fibrosis (CF)test done as a routine part of her prenatal care indicated that she is a carrier of the most common mutant allele.Sheree is stunned,because no one in her family has the disease.She is 26 years old.The genetic counselor would most likely

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The fact that Sheree is a carrier for CF indicates that she inherited one copy of the mutant allele from one of her parents. This means that she has a 50% chance of passing it on to her offspring. CF is an autosomal recessive disorder, meaning that it requires two copies of the mutant allele to cause the disease. Sheree's husband should be tested for CF to determine if he is also a carrier. If he is, then there is a 25% chance that their child will inherit two copies of the mutant allele and have CF. The genetic counselor would likely explain all of this and provide further information and recommendations.

Sheree Is Referred to a Genetic Counselor Because a Cystic