A major way that the human genome differs from the genomes of other primates is that

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Compared to other primate genomes, the human genome has many more duplicated regions. These duplications have played a significant role in the evolution of the human genome by creating new genes and expanding gene families. This has contributed to the development of complex structures and functions in humans that distinguish us from other primates. Deletions and differences in base composition are also present but do not distinguish the human genome from other primate genomes as strongly as the presence of duplicated regions. Larger protein size is not a consistent difference across all species and is not specific to the human genome.

A Major Way That the Human Genome Differs from the Genomes