The loss of a gene that codes for a tumor suppressor protein would predispose certain cells to cancerous transformation and unchecked proliferation.This class of genetic alteration is referred to as:

Question

Quizplus · Accepted Answer

The loss of a gene implies that the genetic material has been deleted, making the correct choice D, i.e. deletion. This deletion can lead to the loss of a tumor suppressor gene, which is an essential safeguard against cancerous transformation. Hence, the other options (point mutation, aneuploidy, and translocation) are not appropriate in this context.

The Loss of a Gene That Codes for a Tumor