Select the true statement about infliximab (Remicade).

Question

Quizplus · Accepted Answer

Infliximab is a monoclonal antibody that binds to and inhibits the activity of tumor necrosis factor (TNF-alpha). TNF-alpha is a mediator of inflammation and immune activation. The main indication for infliximab is in the treatment of Crohn's disease, which is an inflammatory condition of the intestinal tract. Administration of infliximab is associated with an infusion reaction that may occur following IV injection. The reaction can include fever, chills, hives, hypotension, and chest pain. There is also an increased incidence of bacterial infection that occurs in infliximab-treated patients. Other adverse effects include headache, nausea, and GI disturbances.

Select the True Statement About Infliximab (Remicade)