What is the major problem with using large-volume nebulizers for continuous aerosol drug therapy?

Question

Quizplus · Accepted Answer

Large-volume nebulizers can cause drug reconcentration and toxicity, as the nebulizer continuously delivers medication at a high flow rate, leading to an increased concentration of the drug in the respiratory tract. This can lead to adverse effects such as bronchospasm and respiratory distress. Therefore, using small-volume nebulizers or metered-dose inhalers may be a better option for continuous aerosol drug therapy.

What Is the Major Problem with Using Large-Volume Nebulizers for Continuous