The E.coli maltoporin utilizes what has been termed the greasy slide.Which of the following statements best describe the function of the greasy slide?
A) There is a pathway of phospholipids that line the inside of the channel and facilitate transport.
B) A series of aromatic side chains arrange in a helical pattern matching the relative curvature of the protein backbone, thus provided little restriction to transport.
C) Hydroxyl groups on glucose hydrogen bond with polar and charged side chains lining the channel, thus resulting in a series of interactions mimicking a screw-like pathway.
D) Constriction in the channel removes waters of hydration, thus making the substrate more hydrophobic and "greasy."
E) Amino acids side chains lining the channel are small and non-bulky, making steric constriction essentially non-existent.
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