The activity of bacterial glutamine synthetase is
(I)inhibited allosterically by tryptophan.
(II)inhibited allosterically by glucosamine-6-phosphate.
(III)activated by nine allosteric feedback inhibitors.
(IV)altered by covalent modification.

Question

Quizplus · Accepted Answer

Bacterial glutamine synthetase activity is regulated through multiple mechanisms, including allosteric inhibition by metabolites such as tryptophan and glucosamine-6-phosphate, activation by various allosteric feedback inhibitors, and covalent modification, which can alter its activity. This multifaceted regulation allows the enzyme to respond to the cell's metabolic needs and environmental conditions.

The Activity of Bacterial Glutamine Synthetase Is