Which factor has the greatest influence in the development of type 1 diabetes mellitus?

Question

Quizplus · Accepted Answer

The inheritance of the HLA-DR or HLA-DQ tissue types has the strongest association with the development of type 1 diabetes mellitus. Individuals who inherit certain variants of these genes have an increased likelihood of developing the condition. Other factors such as environmental triggers may also contribute to the development of the disease, but genetics play a significant role. Sedentary lifestyle and childhood obesity, mutation in the gene for pancreas development, and advanced maternal age at conception may also be risk factors, but they are not as strongly associated with the development of type 1 diabetes mellitus as genetics.

Which Factor Has the Greatest Influence in the Development of Type