Martha has Alzheimer's disease.She and her daughter Melanie provided care for Martha's mother Margaret when she had severe Alzheimer's disease.Now Melanie,age 57,is showing signs of impaired memory.Melanie's daughter Megan is pregnant with her first child and has contacted a genetic counselor to discuss Alzheimer's risk in her family.Who in this family is the proband?

Question

Quizplus · Accepted Answer

The proband is the individual in a family who brings a genetic disorder to the attention of the medical community, often the first affected family member seeking medical advice. In this scenario, Megan is the proband because she is the one contacting a genetic counselor to discuss the Alzheimer's risk in her family.

Martha Has Alzheimer's Disease