An elderly white male of Scandinavian descent presents with the following hematopoietic studies: MCV = 115 fL, 3+ oval macrocytes, 20% hypersegmented neutrophils. What hematologic condition is suspected?

Question

Quizplus · Accepted Answer

The elevated MCV and presence of oval macrocytes and hypersegmented neutrophils are suggestive of megaloblastic anemia. This is often due to a deficiency in vitamin B12 or folate. Iron-deficiency anemia would not typically present with macrocytic red blood cells. Thalassemia may also cause microcytic or normocytic anemia, but not macrocytic anemia. Anemia of chronic disorders would not typically present with oval macrocytes and hypersegmented neutrophils.

An Elderly White Male of Scandinavian Descent Presents with the Following