In Consequence of Chronic Heavy Alcohol Consumption, Cross-Tolerance May Occur

In consequence of chronic heavy alcohol consumption, cross-tolerance may occur. This refers to

A) a tolerance for many different kinds of alcoholic beverages.
B) a lower responsiveness to certain medications that would normally be processed by the enzymes assisting in alcohol metabolism.
C) an increased responsiveness to other medications that would normally be processed by the enzymes assisting in alcohol metabolism.
D) a reduced tolerance for alcohol when other medications are being processed.