The blue sclera allele has 75 percent penetrance for producing blue sclera, 60 percent penetrance for fragile bones, and 40 percent penetrance for deafness.If these probabilities of penetrance are independent, _______ percent of individuals with the blue sclera allele will have deafness, blue sclera, and fragile bones.

Question

Quizplus · Accepted Answer

To find the percentage of individuals with the blue sclera allele who will have all three conditions (deafness, blue sclera, and fragile bones), multiply the probabilities of each condition's penetrance together because they are independent. Thus, $0.75 \times 0.60 \times 0.40 = 0.18$ or 18%.

The Blue Sclera Allele Has 75 Percent Penetrance for Producing