In a typical long-term potentiation (LTP) study, a stimulating electrode is inserted into the perforant path, while a recording electrode is inserted into the dentate gyrus. LTP is produced in this preparation by delivering a(n) ________ via the stimulating electrode.
A) single high-intensity electrical pulse
B) single low-intensity electrical pulse
C) electrical pulse every minute for 2-3 hours
D) long-duration but low-intensity pulse
E) burst of 100 electrical pulses in a few seconds

Question

Quizplus · Accepted Answer

LTP is typically induced by delivering a high-frequency stimulation, such as a burst of 100 electrical pulses in a few seconds, through the stimulating electrode. This rapid stimulation leads to a long-lasting increase in synaptic strength.

In a Typical Long-Term Potentiation (LTP) Study, a Stimulating Electrode