It is estimated that fifteen to twenty million people lived in Middle America when the Europeans arrived,but after a century of European colonialism,only about 2.5 million remained.

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This statement is true. The estimate of 15 to 20 million pre-Columbian inhabitants of Middle America is widely accepted by historians and anthropologists. However, due to factors such as disease, warfare, and forced labor during European colonialism, the population plummeted to approximately 2.5 million by the end of the 16th century.

It Is Estimated That Fifteen to Twenty Million People Lived