Tay-Sachs disease is a human genetic abnormality that results in cells accumulating and becoming clogged with very large, complex, undigested lipids. Which cellular organelle must be involved in this condition?
A) the endoplasmic reticulum
B) the Golgi apparatus
C) the lysosome
D) mitochondrion
E) membrane-bound ribosomes

Question

Quizplus · Accepted Answer

Tay-Sachs disease is caused by a deficiency of the enzyme hexosaminidase A. As a result, ganglioside GM2, a lipid, accumulates in the lysosomes of neurons, leading to their destruction. Thus, the lysosome is the organelle involved in this condition.

Tay-Sachs Disease Is a Human Genetic Abnormality That Results in Cells