The protective mechanism preventing accumulation of ammonia in most tissues resides in which enzyme?

Question

Quizplus · Accepted Answer

The enzyme responsible for preventing the accumulation of ammonia in most tissues is glutamine synthetase. This enzyme converts toxic ammonia to non-toxic glutamine by combining it with glutamate. Glutamine can then be transported safely to other tissues, such as the liver, where it can be further metabolized. The other enzymes listed are not directly involved in the conversion of ammonia to glutamine.

The Protective Mechanism Preventing Accumulation of Ammonia in Most Tissues