Which of the following statements about heme biosynthesis is correct?

Question

Quizplus · Accepted Answer

The iron atom is inserted after the porphyrin ring has been synthesized. This occurs in the mitochondria and requires multiple enzymes and cofactors to occur. A and D are incorrect because heme synthesis primarily occurs in bone marrow and the liver, and new heme must be synthesized daily to replace old heme that is broken down. B and C are incorrect because succinate and glycine are reactants in the first step, and heme synthesis occurs partially in the cytosol but is completed in the mitochondria.

Which of the Following Statements About Heme Biosynthesis Is Correct