M10621All of the following participate in de novo purine biosynthesis EXCEPT which one?

Question

Quizplus · Accepted Answer

Ribose 1-phosphate does not participate in de novo purine biosynthesis. PRPP, which is derived from ribose 5-phosphate, serves as the ribose sugar backbone to which the purine ring is added. Glycine and inosine 5'-phosphate (IMP, an intermediate in purine synthesis) are directly involved in the pathway, whereas ribose 1-phosphate is not directly used in the synthesis of purine nucleotides.

M10621All of the Following Participate in De Novo Purine Biosynthesis