The chemotherapeutic agent, methotrexate, is a direct inhibitor of
A) thymidylate synthase.
B) aspartate transcarbamoylase.
C) dihydrofolate reductase.
D) PRPP synthase.
E) carbamoyl phosphate synthetase.
Correct Answer:
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Q14: In the de novo biosynthesis of uridine
Q15: The synthesis of UMP requires:
A) formate, aspartate
Q16: The de novo biosynthesis of which of
Q17: Adenylic acid is synthesized in a two
Q18: The distribution of inosine monophosphate (IMP) conversion
Q20: Azaserine inhibits purine biosynthesis at the step
A)
Q21: All carbon and nitrogen atoms of which
Q22: The last two reactions in uric acid
Q23: This enzyme first recognizes allopurinol as a
Q24: The rate of synthesis of AMP is
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