The cephalocaudal and proximodistal rules of development are most correlated with changes in the structure and function of the:

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The cephalocaudal rule states that development proceeds from the head down to the feet, while the proximodistal rule states that development proceeds from the center of the body outwards. Both of these rules are most associated with the development of motor skills and movement pathways, which are controlled by the motor cortex.

The Cephalocaudal and Proximodistal Rules of Development Are Most Correlated