Huntington's disease is a neurodegenerative disease caused by a mutation on a specific gene. Those who have the mutation will develop the disease, and those who do not have the mutation will not develop the disease. The heritability index for Huntington's disease approximates:

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The heritability index measures the proportion of variability in a trait that can be attributed to genetic factors. In the case of Huntington's disease, the presence of the mutation on a specific gene is the only determinant of whether or not the disease will develop, so the heritability index for Huntington's disease is 1, meaning that 100% of the variability in the disease can be explained by genetic factors.

Huntington's Disease Is a Neurodegenerative Disease Caused by a Mutation