The Wife of a Patient Who Has Been Diagnosed with Depression

The wife of a patient who has been diagnosed with depression calls the office and says,"It's been an entire week since he started that new medicine for his depression,and there's no change! What's wrong with him?" Which statement is the best response from the nurse?

A) "The medication may not be effective for him.He may need to try another type."
B) "It may take up to 4 weeks to notice any therapeutic effects.Let's wait a little longer to see how he does."
C) "It sounds like he is tolerant to the drug.I'll check about increasing the dosage."
D) "Some patients never recover from depression.He may not respond to this therapy."