Of the following classes of antidepressant drugs,the one associated with the highest incidence (up to 80% of patients taking the drug)of sexual dysfunction is:

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SSRIs (selective serotonin reuptake inhibitors) are associated with the highest incidence of sexual dysfunction, including difficulty achieving orgasm, decreased libido, and erectile dysfunction. This is due to the medication's effects on serotonin levels in the brain, which can interfere with sexual function. TCAs (tricyclic antidepressants), MAOIs (monoamine oxidase inhibitors), and atypical second-generation antidepressants also have some risk of sexual side effects, but they are generally less significant than those seen with SSRIs.

Of the Following Classes of Antidepressant Drugs,the One Associated with the Highest